Tatiana V. Semenova — Researcher, Center for Sociology of Higher Education, Institute of Education, National Research University Higher School of Economics. 
Address: Bld. 10, 16 Potapovsky Ln, 101000 Moscow, Russian Federation. E-mail: tsemenova@hse.ru 

Susanna S. Sologova — Candidate of Sciences in Biology, Associate Professor of the Department of Pharmacology, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University. E-mail: sologova_s_s@staff.sechenov.ru (сorresponding author) 

Sergey P. Zavadsky — Candidate of Sciences in Pharmacology, Associate Professor of the Department of Pharmacology, I.M. Sechenov First Moscow State Medical University. E-mail: zavadskiy_s_p@staff.sechenov.ru 

Ekaterina M. Grigorevskikh — Senior Lecturer of the Department of Pharmacology, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University. E-mail: grigorevskikh_e_m@staff.sechenov.ru 

Arus G. Margaryan — Assistant of the Department of Pharmacology, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University. E-mail: margaryan_a_g@staff.sechenov.ru 

Daria A. Trashchenkova — Assistant of the Department of Pharmacology, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University. E-mail: trashchenkova_d_a@staff.sechenov.ru 

Esma I. Avakyan — Candidate of Sciences in Medicine, Director of the Representative Office of the International Association for Medical Education, Assistant of the Department of Faculty Therapy No 1, I.M. Sechenov First Moscow State Medical University. E-mail: avakyan_e_i@staff.sechenov.ru 

Dmitry M. Sokhin — graduate of the Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University. E-mail: verbose-1@rambler.ru 

Tatiana M. Litvinova — Candidate of Sciences in Pharmacology, Vice-Rector for Academic Affairs, Head of the Department of Pharmacy, I.M. Sechenov First Moscow State Medical University. E-mail: litvinova_t_m_1@staff.sechenov.ru 

Elena A. Smolyarchuk — Candidate of Sciences in Medicine, Head of the Center for Clinical Study of Medicines, Head of the Department of Pharmacology, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University. E-mail: smolyarchuk_e_a@staff.sechenov.ru 

Address: Bld. 2, 8 Trubetskaya St., 119991 Moscow, Russian Federation. 

The forced massive transition of universities to distance learning due to the pandemic has raised questions about the effectiveness of online education in general and video lectures in particular. Research shows that video lectures are either comparable or less effective than face-to-face lectures. In this work, based on the data collected as part of the experiment, we compare two lecture formats (videolecture and face-to-face lecture) based on the educational results of students, and also evaluate the combined lecture format. The experiment involved 151 second-year students in the direction of training “Pharmacy” of Sechenov University. The field experiment was carried out in the spring semester of the 2020-2021 academic year in three stages. At the first stage, some of the students listened to a face-to-face lecture, and some - a video lecture. At the second stage, both groups were swapped. At the final stage, both groups listened to a combined lecture. Our research has shown that a video lecture and a face-to-face lecture are the same in their effectiveness: on average, students received the same educational results as a result of mastering the lecture material. At the same time, the combined lecture led to an increase in the educational results of students - after the combined lecture format, students received a higher score for the post-test, and also showed a greater increase in the level of knowledge. The results of the study will be especially relevant for the administration of universities responsible for the implementation of online learning, and teachers who conduct lectures.